The Mouse Nervous System.

The Mouse Nervous System provides a comprehensive account of the central nervous system of the mouse. The book is aimed at molecular biologists who need a book that introduces them to the anatomy of the mouse brain and spinal cord, but also takes them into the relevant details of development and org...

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Bibliographic Details
Main Author: Watson, Charles.
Other Authors: Paxinos, George., Puelles, Luis.
Format: eBook
Language:English
Published: Saint Louis : Elsevier Science & Technology, 2011.
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Table of Contents:
  • Front Cover
  • The Mouse Nervous System
  • Copyright
  • Dedication
  • Contents
  • List of Contributors
  • Preface
  • Acknowledgments
  • Section A - Development
  • Chapter 1 - Molecular Regionalization of the Developing Neural Tube
  • Introduction
  • Morphogenesis of the Neural Tube
  • Dorso-Ventral (DV) Patterning in the Neural Tube
  • Antero-Posterior (AP) Patterning in the Neural Tube
  • Secondary Organizers Control Molecular Regionalization
  • Diencephalic Regionalization: How the Diencephalon Creates its Structural Complexity
  • The Diencephalic Transcriptome Map Supports the Prosomeric Model
  • List of Abbreviations
  • References
  • Chapter 2 - Gene Targeting
  • The Pioneering Experiments
  • Mouse Strains and Stem Cells used in Gene Knockout Technology
  • Gene Targeting in other Rodent Species
  • Strategies to Specific Gene Inactivation
  • Conditional Gene Inactivation and Genetic Labeling in the Nervous System
  • Genetic Tools for Functional Dissection of Neuronal Circuits
  • References
  • Chapter 3 - Genetic Neuroanatomy
  • Genetic Neuroanatomy
  • Use of Genetic Inducible Fate Mapping to Relate Embryonic Genetic Neuroanatomy to Adult Neural Structures
  • Dissecting the Three Dimensional Organization and Circuitry of the Cerebellum Using Genetic Fate Mapping
  • New Insights into Neurogenesis and Specification of Cell Types using Genetic Fate Mapping
  • GIFM as an Approach for Identifying and Studying Adult Stem Cells
  • Future Applications of Fate Mapping of Genetic Neuroanatomy
  • References
  • Section B - Structure
  • Chapter 4 - Neocortex
  • Role of the Neocortex
  • Structure of Neocortex
  • Cellular Constituents
  • Function of the Neocortex
  • Regions of the Neocortex
  • Strain Variation
  • Mouse-Human Homology
  • References
  • Chapter 5 - Hippocampus
  • Introduction
  • Cytoarchitectonics and Cell Types
  • Connectivity.
  • Effects of Strain, Species, and Environment on Architecture
  • Conclusions
  • References
  • Chapter 6 - Piriform Cortex and Amygdala
  • Introduction
  • Piriform Cortex and Endopiriform Nucleus
  • The Amygdala: Structure and Organization
  • Functional Neuroanatomy of the Amygdala
  • References
  • Chapter 7 - Subpallial Structures
  • Introduction
  • General Overview of Major Subpallial Structures and Fiber Tracts
  • Subpallial Development - Early Steps: Specification, Parcellation and Morphogenesis
  • Lateral Striatal (LGE) Derivatives and Formation of Mature Striatal Structures
  • Lateral Pallidal (MGE) Derivatives and Formation of Mature Pallidal Structures
  • Preoptic Derivatives and Mature Preoptic Region
  • Septum
  • Implications for Understanding the Functional Organization of the Subpallium
  • Abbreviations
  • References
  • Chapter 8 - Hypothalamus
  • Introduction
  • Neural Plate Topology of the Hypothalamus
  • Early Developmental Molecular Subdivisions of the Hypothalamus: The Fundamental Progenitor Areas
  • Subthalamus
  • Hypothalamic Nuclei Derived from the Diverse Progenitor Domains
  • Organization of Gabaergic and Glutamatergic Cell Populations
  • Major Hypothalamic Fiber Tracts
  • Literature on the Mouse Hypothalamus
  • References
  • Chapter 9 - Diencephalon
  • Prosomere 1
  • Prosomere 2
  • Prosomere 3
  • References
  • Chapter 10 - Midbrain
  • Specification of the Midbrain
  • Antero-Posterior Organization of the Midbrain
  • Dorso-Ventral Organization of the Midbrain
  • Neuronal Populations of the Midbrain
  • References
  • Chapter 11 - Cerebellum
  • External Gross Anatomy
  • Cerebellar Lobules and Folial Pattern
  • Molecular and Genetic Parcellation of Cerebellar Lobules
  • Cell Types and Microcircuitry
  • Afferent Fibers Projecting to the Cerebellum
  • Molecular Organization of the Cerebellum
  • Cerebellar Nuclei.
  • Morphogenesis of the Cerebellum
  • The Germinal Zones in the Developing Cerebellum
  • The Precerebellar Nuclei
  • Summary
  • References
  • Chapter 12 - Hindbrain
  • Subdivisions of the Hindbrain - the Isthmus, Rhombomeres, and Cerebellum
  • Neuronal Groupings in the Longitudinal Core of the Hindbrain
  • Sensory Nuclei of the Hindbrain
  • Nuclei Associated with Visceral Sensation
  • Reticular Nuclei of the Hindbrain
  • Monoamine Nuclei of the Hindbrain
  • Cholinergic Nuclei
  • Nuclei that Control Respiration and Other Visceral Functions
  • Major Fiber Tracts of the Hindbrain
  • References
  • Chapter 13 - Spinal Cord
  • Introduction
  • Gross Anatomy of the Mouse Spinal Cord
  • Cytoarchitecture of the Mouse Spinal Cord
  • The Distribution of Major Neuronal Transmitters in the Mouse Spinal Cord
  • Ascending and Descending Pathways of the Spinal Cord
  • Projections from the Brain to the Spinal Cord
  • Spinal Cord Development
  • Blood Supply of the Spinal Cord
  • The Allen Spinal Cord Atlas
  • References
  • Chapter 14 - Vascular Supply
  • Introduction
  • Anatomy
  • Blood Flow Imaging and Functional Localization
  • References
  • Chapter 15 - Magnetic Resonance Imaging of the Mouse Brain
  • Resolution and Contrast are Two Important Factors in MRI
  • Intrinsic and Extrinsic Contrast Generation
  • In Vivo and Ex Vivo MRI have Relative Advantages and Disadvantages
  • There are Application Studies in Which MRI Plays a Vital Role
  • Summary
  • References
  • Section C - Motor and Sensory Systems
  • Chapter 16 - Motor Nuclei of the Cranial Nerves
  • Oculomotor Nucleus
  • Edinger-Westphal Nucleus
  • Trochlear Nucleus
  • Motor Trigeminal Nucleus
  • Abducens Nucleus
  • Facial Motor Nucleus
  • Neurons Projecting to the Sense Organs of the Labyrinth
  • Superior and Inferior Salivatory Nuclei
  • Nucleus Ambiguus
  • Dorsal Motor Nucleus of the Vagus
  • Hypoglossal Nucleus.
  • The Spinal Accessory Motor Neurons
  • References
  • Chapter 17 - Visceral Motoneurons
  • The Autonomic Nervous System Plays a Pivotal Role in Homeostasis and Reproduction
  • General Anatomical Features
  • Chemical Coding of Autonomic Pathways
  • Preganglionic Neurons
  • Postganglionic Neurons
  • Major Autonomic Pathways
  • Conclusions
  • References
  • Chapter 18 - Neurosecretory Nuclei of the Hypothalamus and Preoptic Area
  • Paraventricular and Supraoptic Nuclei
  • The Anatomy of Pa and SO in the Mouse
  • Functions of the Hypothalamic Neurosecretory System
  • Regulation of Pa Activity
  • Regulation of SO Activity
  • Control of Gonadotrophin and Prolactin Secretion
  • References
  • Chapter 19 - Motor Cortex
  • Introduction
  • Primary Motor Cortex (M1)
  • Secondary Motor Cortex (M2)
  • Motor Functions of Anterior Cingulate Cortex
  • Behavioral Consequences of Motor Cortex Lesions: Impairments and Recoveries
  • Motor Map Plasticity in Rodent Models of Seizures
  • References
  • Chapter 20 - Hypothalamic Goal-directed Behavior - Ingestive, Reproductive and Defensive
  • Introduction
  • The Behavior Control Column
  • Ingestive Behaviors: Drinking and Eating
  • Reproductive Behaviors
  • Defensive Behaviors
  • Concluding Remarks
  • References
  • Chapter 21 - The Somatosensory System
  • Somatosensory Receptor Types
  • The Trigeminal System
  • Somatosensory Thalamus
  • Somatosensory Cortex
  • References
  • Chapter 22 - Gustatory
  • Introduction
  • Peripheral Viscerosensation
  • Brain Stem Viscerosensory Systems
  • Forebrain Viscerosensory Pathways
  • List of Abbreviations
  • References
  • Chapter 23 - Pain
  • Introduction
  • The Nociceptor
  • Molecular Mechanisms in Nociceptor Function
  • Nociceptor Development
  • Spinal Cord Dorsal Horn
  • Descending Projections to Dorsal Horn Neurons
  • Representation of Pain in the Cerebral Cortex
  • Conclusion.
  • References
  • Chapter 24 - Auditory System
  • Introduction
  • Sound Transduction in the Ear
  • The Organ of Corti
  • The Cochlear Nuclear Complex (CNC)
  • The Superior Olivary Complex (SOC)
  • The Nuclei of the Lateral Lemniscus (NLL)
  • The Inferior Colliculus (IC)
  • Cytoarchitecture of the Inferior Colliculus
  • The Medial Geniculate Body (MG)
  • The Auditory Cortex (AC)
  • The Descending Auditory Pathway
  • Abbreviation List
  • References
  • Chapter 25 - Visual System
  • The Eye and Retina
  • Photoreceptor Layer
  • Horizontal Cells
  • The Inner Nuclear Layer - Bipolar and Amacrine Cells
  • Retinal Ganglion Cell Layer
  • Glial Cells in the Retina
  • The Blood Supply to the Mouse Retina
  • The Optic Nerve
  • The Optic Chiasm and Optic Tract
  • The Central Projections of the Retina
  • The Pretectum and Accessory Optic Tract Nuclei
  • The Superior Colliculus
  • The Dorsal Lateral Geniculate Nucleus
  • Visual Cortex
  • References
  • Chapter 26 - The Olfactory System
  • Introduction
  • Types of Olfactory Neuroepithelium
  • Olfactory Bulb
  • Lateral Olfactory Tract and Anterior Commissure
  • Conclusions
  • References
  • Chapter 27 - Vestibular System
  • Introduction
  • Periphery
  • Central
  • References
  • Section D - Behavioral and Emotional States
  • Chapter 28 - The Basal Forebrain Cholinergic Projection System in Mice
  • Introduction
  • Neuron Types in the Basal Forebrain
  • Efferent, Afferent, Intrinsic Connections and Organization
  • Development and Molecular Specification of Basal Forebrain Cholinergic Projection Neurons
  • Transgenic Mouse Models of Neurodegeneration of Basal Forebrain Cholinergic Neurons
  • Trophic Factor Maintenance and the P75 Neurotrophin Receptor
  • Concluding Remarks
  • References
  • Chapter 29 - An Introduction to the Neurobiology of Emotions and Social Behavior
  • Emotions
  • Social Behavior
  • Conclusion
  • References.
  • Chapter 30 - Prefrontal Cortex.